Ann Louw Selected Research

cyclopia sequence

1/2018	Chemoprevention of LA7-Induced Mammary Tumor Growth by SM6Met, a Well-Characterized Cyclopia Extract.
10/2016	The phytoestrogenic Cyclopia extract, SM6Met, increases median tumor free survival and reduces tumor mass and volume in chemically induced rat mammary gland carcinogenesis.
5/2013	Phytoestrogenic potential of Cyclopia extracts and polyphenols.
1/2013	Cyclopia extracts act as ERα antagonists and ERβ agonists, in vitro and in vivo.
11/2008	Selective extraction of Cyclopia for enhanced in vitro phytoestrogenicity and benchmarking against commercial phytoestrogen extracts.
5/2007	Evaluation of the phytoestrogenic activity of Cyclopia genistoides (honeybush) methanol extracts and relevant polyphenols.

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Ann Louw Research Topics

Disease

6	cyclopia sequence 01/2018 - 05/2007
4	Inflammation (Inflammations) 01/2022 - 11/2005
3	Breast Neoplasms (Breast Cancer) 10/2016 - 05/2007
2	Neoplasms (Cancer) 01/2018 - 10/2016
1	Glucocorticoid Receptor Deficiency 01/2021
1	Carcinogenesis 10/2016
1	Hepatocellular Carcinoma (Hepatoma) 11/2010

Drug/Important Bio-Agent (IBA)

2	GlucocorticoidsIBA 01/2022 - 01/2018
2	Glucocorticoid Receptors (Glucocorticoid Receptor)IBA 01/2021 - 01/2018
2	Estrogens (Estrogen)FDA Link 01/2018 - 01/2013
2	PolyphenolsIBA 05/2013 - 05/2007
2	Phytoestrogens (Phytoestrogen)IBA 01/2013 - 11/2008
1	Biomarkers (Surrogate Marker)IBA 01/2018
1	LipidsIBA 01/2018
1	Fulvestrant (Faslodex)FDA Link 01/2018
1	Letrozole (Femara)FDA LinkGeneric 01/2018
1	Estrogen ReceptorsIBA 01/2018
1	Tamoxifen FDA LinkGeneric 01/2018
1	Methylnitrosourea (N-Methyl-N-nitrosourea)IBA 10/2016
1	Estradiol Congeners (Synthetic Estrogens)IBA 01/2013
1	TeaIBA 01/2013
1	Messenger RNA (mRNA)IBA 11/2010
1	Acute-Phase Proteins (Acute-Phase Protein)IBA 11/2010
1	Glucose (Dextrose)FDA LinkGeneric 11/2010
1	Proteins (Proteins, Gene)FDA Link 11/2010
1	Interleukin-6 (Interleukin 6)IBA 11/2010
1	Methanol (Carbinol)IBA 05/2007
1	Dexamethasone (Maxidex)FDA LinkGeneric 11/2005

Therapy/Procedure

2	Chemoprevention 01/2018 - 10/2016
1	Therapeutics 01/2018